Journal article
Green method for recovery of cannabinoids from Cannabis sativa flowers: pH-controlled aqueous leaching
HT Lu, W Li, MA Deseo, GW Stevens, A Bacic, MS Doblin, KA Mumford
Separation and Purification Technology | Published : 2023
Abstract
Cannabis sativa is a remarkable plant containing a wide variety of valuable secondary metabolites, especially cannabinoids, which are valued for their clinical relevance. In this investigation, an efficient and environmentally friendly method to recover cannabinoids from cannabis plant tissues using organic solvent-free pH-controlled solution has been developed. The impact of leaching pH and solid/liquid ratios on the recovery of thirteen acidic and neutral cannabinoids from a wide range of cannabis plant tissues, which are either high tetrahydrocannabinol (THC) or high cannabidiol (CBD) cultivars in fresh, dried and decarboxylated forms, was investigated. The results revealed acidic cannabi..
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Awarded by Australian Research Council
Funding Acknowledgements
The authors would like to acknowledge the funding provided by the Australian Research Council to the Industrial Transformation Research Hub for Medicinal Agriculture (ARC MedAg Hub; IH180100006) and a Linkage Program grant (LP160101317) , University of Melbourne, La Trobe University and Cann Group Ltd. (Victoria) for this project. We would like to thank Cann Group Ltd for access to their facilities and provision of plant materials. We also thank Dr. Ricarda Jost, Dr. Matthew Welling and Ms. Amelia Pegg for their assistance in harvesting cannabis materials.